ProteinLIPS

Prediction of locally unstable segments of proteins

ProteinLIPS scans protein structures, computes packing densities and surface polarities, and predicts the locally unstable segments which are likely to be the first parts of the protein to unfold, the last parts to fold or to be involved in protein dynamics. You can query using PDB codes or keywords, e.g. if interested in a family of proteins.

ProteinLIPS

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Examples: 1BWM, HYDROLASE, LYSOZYME, HOMO SAPIENS, CHICKEN
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Examples: HYDROLASE, LYSOZYME, HOMO SAPIENS, CHICKEN
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Examples: HYDROLASE, LYSOZYME, HOMO SAPIENS, CHICKEN
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Citation

If you find our server useful to your research please consider also citing the following article:

  1. VE Angarica, J Sancho (2012). Protein dynamics governed by interfaces of high polarity and low packing density. PloS One 7 (10), e48212. [PUBMED] [PDF]
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